Many adults over 60 notice their legs feeling heavier, stairs becoming more challenging, or a slight wobble when standing. These changes can make everyday activities feel harder and raise concerns about balance and independence. Research shows that nutrient levels, including certain vitamins, play a role in muscle function, nerve health, and bone support as we age. But there’s an interesting detail about timing that many people overlook—keep reading to learn more about it toward the end.

Understanding Leg Strength Challenges in Older Adults
As we get older, it’s common to experience gradual changes in leg strength and balance. According to CDC data, more than one in four adults aged 65 and older reports falling each year, often linked to factors like reduced muscle mass or slower nerve signals.
Studies suggest that low levels of key vitamins can contribute to these issues. For example:
- Vitamin B12 supports healthy nerve function, which is important for steady movement.
- Vitamin D helps with calcium absorption and muscle performance.
- Vitamin K2 aids in directing calcium to bones and away from arteries.
Research, including reviews in journals like Nutrients and the Journal of Gerontology, indicates that maintaining adequate levels of these vitamins may support overall leg health and mobility.
But here’s something important: The time of day you take supplements might influence how well your body uses them. More on that later.
Why Vitamin B12 Matters for Nerve Health and Steady Steps
Vitamin B12 is essential for maintaining healthy nerves that send signals to your muscles. Low B12 levels are common in older adults due to reduced absorption, and studies link deficiency to symptoms like tingling, numbness, or unsteady walking.
Research from sources like Harvard Health and PMC articles shows that B12 deficiency can affect balance and increase fall risk in the elderly. Supplementing with forms like methylcobalamin may help support nerve conduction, based on neurological studies.
Many experts recommend checking B12 levels, especially if you experience leg tingling or difficulty with uneven surfaces.
The Role of Vitamin D in Muscle Function and Daily Mobility
Vitamin D receptors are found in muscle tissue, and adequate levels are associated with better muscle strength. Observational studies and some trials suggest that vitamin D supports physical performance, particularly in those with low levels.
A meta-analysis in the Journal of Cachexia, Sarcopenia and Muscle noted potential benefits for muscle health, though results vary. Pairing vitamin D with healthy fats (like from a meal) can improve absorption.
Quick tip: If standing from a chair feels effortful, discussing vitamin D levels with your doctor could be worthwhile.

How Vitamin K2 Supports Calcium Balance and Bone Health
Vitamin K2 helps activate proteins that direct calcium to bones and teeth, supporting skeletal strength. Studies, including those in Osteoporosis International, indicate that K2 may contribute to better bone geometry and reduced fracture risk when combined with vitamin D.
This synergy is key—vitamin D increases calcium absorption, while K2 helps ensure it’s used properly.
Potential Benefits of Taking These Vitamins in the Evening
Here’s the detail many miss: Some research explores whether evening intake aligns better with the body’s natural repair processes during sleep.
- Muscle protein synthesis and recovery often peak overnight.
- Limited studies on vitamin D timing suggest consistency matters most, but taking fat-soluble vitamins with dinner (containing fats) aids absorption.
- Anecdotal and small trials hint at bedtime dosing supporting overnight nutrient use, though more evidence is needed.
Research in journals like Nutrients discusses how nighttime supplementation might complement rest phases.
Common Ways These Vitamins May Support Leg Health
Based on scientific reviews:
- Improved nerve signaling (B12)
- Enhanced muscle performance (Vitamin D)
- Better calcium utilization for bones (K2)
- Potential reduction in nighttime discomfort
- Support for overall balance and endurance
Studies show mixed but promising results when levels are optimized.
Comparison: Morning vs. Evening Supplementation Considerations
| Aspect | Morning Intake | Evening Intake |
|---|---|---|
| Absorption | Good with breakfast fats | Enhanced with dinner; aligns with repair |
| Convenience | Fits busy routines | Part of bedtime routine |
| Research Support | Standard recommendation | Emerging for overnight benefits |
| Potential Drawbacks | May miss fat source if skipping meals | Rare sleep interference in sensitive people |
Evidence emphasizes consistency and pairing with food over strict timing.
Practical Steps to Explore These Vitamins Safely
If you’re considering supplements:
- Get blood levels tested for B12, D, and others.
- Choose quality forms: Methylcobalamin for B12, D3 for vitamin D, MK-7 for K2.
- Take with a meal containing fats for better absorption.
- Start low and monitor how you feel.
- Combine with gentle activity, like walking or balance exercises.
Many find evening dosing convenient, but choose what fits your schedule.

Conclusion
Supporting leg strength and balance after 60 involves nutrition, activity, and lifestyle. Vitamins B12, D3, and K2 show promise in research for nerve, muscle, and bone health, with evening intake potentially offering a practical edge. Focus on evidence-based habits for long-term mobility.
Frequently Asked Questions
1. When is the best time to take these vitamins?
Consistency is key. Many take them with dinner for absorption, or in the evening to align with rest. Consult your doctor for personalized advice.
2. Can these vitamins prevent falls?
They may support factors like balance and strength, but no supplement guarantees prevention. Combine with exercise and home safety measures.
3. Are there risks to supplementing?
High doses can interact with medications (e.g., K2 with blood thinners). Always test levels first and discuss with a healthcare provider.
Disclaimer: This article is for informational purposes only and is not medical advice. Supplements do not diagnose, treat, or cure any condition. Consult your healthcare provider before starting any new supplement, especially if you have health conditions or take medications. Get nutrient levels tested when possible.